Roadmap for the development of candidate vaccines for FMD

What are we trying to achieve and why? What is the problem we are trying to solve?

There are a range of viruses’ strains which differ in terms of virulence. Having virus genome sequences is essential for
identifying the host pathogen interactions and how this can be manipulated. Establishing the genomic differences of the various strains will assist in the identification of virulence mechanisms

What are the scientific and technological challenges (knowledge gaps needing to be addressed)?

Understand the bases for functional genomic and predictive genomics

What approaches could/should be taken to address the research question?

What else needs to be done before we can solve this need?

Existing knowledge including successes and failures