Roadmap for the research to underpin the development of control strategies for FMD

What are we trying to achieve and why? What is the problem we are trying to solve?

To develop low cost commercially available disinfectants for  use in the inactivation of FMDV on contaminated surfaces found in farm settings and other susceptible environments.

What are the scientific and technological challenges (knowledge gaps needing to be addressed)?

Development of low cost commercially available disinfectants for use in the inactivation of FMDV on contaminated surfaces found in farm settings and other susceptible environments.

What approaches could/should be taken to address the research question?

What else needs to be done before we can solve this need?

Existing knowledge including successes and failures

Sodium hydroxide (2%), sodium carbonate (4%), and citric acid (1 to 2%, depending on the surface to be treated) have
been reported to be effective disinfectants for FMDV. Less ideal disinfectants include iodophors, quaternary ammonium compounds, hypochlorite, and phenols, because they rapidly lose the ability to disinfect in the presence of
organic matter. Surfactants alone have little efficacy against FMDV due to the non-enveloped structure of the virus. There are newer disinfectants that are not as corrosive, including Virkon-S®, a chlorinated compound.