Influenza roadmap:
Diagnostic Tests
Roadmap for the development of diagnostic test for influenza
Download Influenza-diagnostic-development-roadmapB
Genetic
Genetic
Research Question
- Rapid, cost-effective tools for
– genetic detection
– Sequence analysis and characterization
– Sequence reporting/databases that communicate with each other (I.e., sequences from one database can be downloaded and analyzed in another without loss of integrity)
Research Gaps and Challenges
- Systematic approaches for analyzing and reporting viral genome sequences
- Issues around samples most relevant for infection in different species with swabs alone not necessarily enabling detection
- Approaches that are specific i.e. need to know what you have before you can test
Solution Routes
- Effective deployment of 3rd -gen sequencing technologies for both wet and dry-lab protocols, allowing point-of-incidence analysis
- Rapid characterization of variants circulating in the field via high throughput point-of-care technology
- Improve sensitivity and purification methods for whole-genome sequencing
- Evaluation of whole genome sequencing platforms
- Develop highly multiplexed PCR assays
- Improved and easily employed metagenomic pipelines
- Commercialization or Increased availability of novel technology like viability PCR tests
Dependencies
- Training of more bio informaticists to mine and interpret the data
- Understand the relationship between genetic detection and transmission IRL
- Improved reference databases/faster assignment of genetic clades as they appear
- Turnkey solutions to allow use in more veterinary labs
- Reduce complexity of testing procedure to make it more accessible
Projects
What activities are planned or underway?
Protect wildlife from livestock diseases.
Planned Completion date 07/10/2022
Participating Country(s):
Netherlands
Dynamics of sustainability in integrated agriculture : aquaculture systems in the Mekong Delta
Planned Completion date 21/10/2024
Participating Country(s):
Netherlands