Influenza roadmap:
Vaccines
Roadmap for the development of candidate vaccines for influenza
Download Influenza-vaccine-development-roadmap5
DNA/RNA
DNA/RNA vaccines
Research Question
- Efficacious and safe nucleic acid-based vaccines
Research Gaps and Challenges
- Durable protection
- Identification of the most suitable antigens and its genetic code.
- Adjuvants for DNA/RNA vaccines
- Storage and delivery of vaccine
- Cost-effectiveness
Solution Routes
- Enhanced immunogenicity using molecular adjuvants
- Production and trial (in-ovo trials) of the most suitable antigens
Dependencies
- Develop adjuvants that can increase immunogenicity
State Of the Art
- There are mRNA candidate vaccines currently under clinical trials. DNA
vaccine licensed in US but not currently in use. RNA vaccine have
limited use in LMIC due to storage issues
Projects
What activities are planned or underway?
Protect wildlife from livestock diseases.
Planned Completion date 07/10/2022
Participating Country(s):
Netherlands
Impact of host age on viral and bacterial communities in a waterbird population.
Planned Completion date 01/11/2022
Participating Country(s):
Netherlands