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Influenza roadmap:
Vaccines

Roadmap for the development of candidate vaccines for influenza

Download Influenza-vaccine-development-roadmap

5

DNA/RNA

Dependencies

Next steps

DNA/RNA vaccines

Research Question

  • Efficacious and safe nucleic acid-based vaccines

Research Gaps and Challenges

  • Durable protection
  • Identification of the most suitable antigens and its genetic code.
  • Adjuvants for DNA/RNA vaccines
  • Storage and delivery of vaccine
  • Cost-effectiveness

Solution Routes

  • Enhanced immunogenicity using molecular adjuvants
  • Production and trial (in-ovo trials) of the most suitable antigens

Dependencies

  • Develop adjuvants that can increase immunogenicity

State Of the Art

  • There are mRNA candidate vaccines currently under clinical trials. DNA
    vaccine licensed in US but not currently in use. RNA vaccine have
    limited use in LMIC due to storage issues

Projects

What activities are planned or underway?

Protect wildlife from livestock diseases.

Planned Completion date 07/10/2022

Participating Country(s):

NetherlandsIconNetherlands

Dynamics of sustainability in integrated agriculture : aquaculture systems in the Mekong Delta

Planned Completion date 21/10/2024

Participating Country(s):

NetherlandsIconNetherlands