Influenza roadmap:
Vaccines
Roadmap for the development of candidate vaccines for influenza
Download Influenza-vaccine-development-roadmap6
Subunit vaccines
Subunit vaccines
Research Question
- Immunogenic subunit vaccines and optimal expression systems
Research Gaps and Challenges
- Low immunogenicity
- Can be developed as multivalent with several mixture of antigens.
- Cost effective
- Still fairly empirical with respect to success of in the antigenic/stability
properties of the antigens - Adjuvants in general (killed vaccines and other vaccine platforms) need
further research
Solution Routes
- Use of adjuvants that could increase immunogenicity
- Production and trial of the most suitable antigens
Dependencies
- Develop adjuvants that could increase immunogenicity
- For commercialization, adjuvant withdrawal time is a major hurdle
depending on species and use
State Of the Art
- Baculous virus
Projects
What activities are planned or underway?
Protect wildlife from livestock diseases.
Planned Completion date 07/10/2022
Participating Country(s):
Netherlands
Dynamics of sustainability in integrated agriculture : aquaculture systems in the Mekong Delta
Planned Completion date 21/10/2024
Participating Country(s):
Netherlands