Home Influenza [Subunit vaccines] Subunit vaccines
Influenza roadmap:
Vaccines

Roadmap for the development of candidate vaccines for influenza

Download Influenza-vaccine-development-roadmap

6

Subunit vaccines

Dependencies

Next steps

Subunit vaccines

Research Question

  • Immunogenic subunit vaccines and optimal expression systems

Research Gaps and Challenges

  • Low immunogenicity
  • Can be developed as multivalent with several mixture of antigens.
  • Cost effective
  • Still fairly empirical with respect to success of in the antigenic/stability
    properties of the antigens
  • Adjuvants in general (killed vaccines and other vaccine platforms) need
    further research

Solution Routes

  • Use of adjuvants that could increase immunogenicity
  • Production and trial of the most suitable antigens

Dependencies

  • Develop adjuvants that could increase immunogenicity
  • For commercialization, adjuvant withdrawal time is a major hurdle
    depending on species and use

State Of the Art

  • Baculous virus

Projects

What activities are planned or underway?

Protect wildlife from livestock diseases.

Planned Completion date 07/10/2022

Participating Country(s):

NetherlandsIconNetherlands

Dynamics of sustainability in integrated agriculture : aquaculture systems in the Mekong Delta

Planned Completion date 21/10/2024

Participating Country(s):

NetherlandsIconNetherlands