Influenza roadmap:
Control Strategies
Roadmap for the development of disease control strategies for influenza
Download Influenza-control-development-roadmap10
Coinfection
Next steps
Coinfection
Research Question
- Impact of influenza virus infection on co-infection with different viruses or bacteria and vice versa
Research Gaps and Challenges
- Effects of co-infection with different viruses or bacteria
- Coinfection often leads to misdiagnosis
- Coinfection could lead to reassortment, increase shedding and increase susceptibility?
Solution Routes
- Experimental and field studies particularly with representative avian species (wild & poultry species) and for pigs
- Assess added value of vaccination against co-infecting pathogens to prevent influenza infections
- Models that include coinfection risks/phenotypes/outcomes and
- Suitable panel assay for respiratory viruses
- Whole genome sequencing in co-infected populations to identify the possible pathogens that could dampen the immune system and result in persistent low-level infections
- Investigate regional approach instead of country-level approach in territories with similar trade systems
- Understanding market system and role in co-infection and vice versa
- Penside tests for co-infections to improve field actions
Dependencies
- Knowledge of/studies of the potential co-infectors across the globe
- Good differential diagnosis protocols
- Improved tests to inform/predict protection
- Well developed and integrated vaccination programs
Projects
What activities are planned or underway?
Development of Vaccines for HPAI in Cattle, Turkey, Pigs, and Small Ruminants and Food Safety Studies Related to HPAI Virus in Food Products
Planned Completion date 25/08/2029
Source Countries:
United States
Automated non-invasive Detection of Surface Contamination and Optimizing Surface Biofilm Removal Conditions in Large-Scale Food Processing Equipment
Planned Completion date 31/08/2028
Source Countries:
United States