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Influenza roadmap:
Control Strategies

Roadmap for the development of disease control strategies for influenza

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10

Coinfection

Coinfection

Research Question

  • Impact of influenza virus infection on co-infection with different viruses or bacteria and vice versa

Research Gaps and Challenges

  • Effects of co-infection with different viruses or bacteria
  • Coinfection often leads to misdiagnosis
  • Coinfection could lead to reassortment, increase shedding and increase susceptibility?

Solution Routes

  • Experimental and field studies particularly with representative avian species (wild & poultry species) and for pigs
  • Assess added value of vaccination against co-infecting pathogens to prevent influenza infections
  • Models that include coinfection risks/phenotypes/outcomes and
  • Suitable panel assay for respiratory viruses
  • Whole genome sequencing in co-infected populations to identify the possible pathogens that could dampen the immune system and result in persistent low-level infections
  • Investigate regional approach instead of country-level approach in territories with similar trade systems
  • Understanding market system and role in co-infection and vice versa
  • Penside tests for co-infections to improve field actions

Dependencies

  • Knowledge of/studies of the potential co-infectors across the globe
  • Good differential diagnosis protocols
  • Improved tests to inform/predict protection
  • Well developed and integrated vaccination programs

Projects

What activities are planned or underway?

Protect wildlife from livestock diseases.

Planned Completion date 07/10/2022

Participating Country(s):

NetherlandsIconNetherlands

Dynamics of sustainability in integrated agriculture : aquaculture systems in the Mekong Delta

Planned Completion date 21/10/2024

Participating Country(s):

NetherlandsIconNetherlands