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Cell-mediated immunity

Cell-mediated immunity

Research Question

  • Identify the role of cellular immune response to protect from infection

Research Gaps and Challenges

  • Understand the role (and duration) of the cellular immune response in protection and in the pathogenesis of different influenza strains
  • Understanding of the cellular immune response of chickens to HPAI and its significance during infection

Solution Routes

  • Role of cell mediated immunity in protection following infection in wild birds versus poultry, and in particular its role in determining transmission
  • Characterization of the post-vaccination adaptive cellular immune response in swine
  • Passive transfer studies
  • Study on LPAI capacity to replicate within birds in extra respiratory and extra GI sites and the relative alteration of immunity response
  • Improved diagnostic tools to measure the cellular immune response that allows us to predict protection
    Interferon type I and type II needs to be measure
  • Which phenotype of immune cells respond to infection of vaccines

Projects

What activities are planned or underway?

Protect wildlife from livestock diseases.

Planned Completion date 07/10/2022

Participating Country(s):

NetherlandsIconNetherlands

Dynamics of sustainability in integrated agriculture : aquaculture systems in the Mekong Delta

Planned Completion date 21/10/2024

Participating Country(s):

NetherlandsIconNetherlands