Coronaviruses roadmap:
Diagnostic Tests
Roadmap for the development of diagnostic tests for coronaviruses
Download 202410 Draft Coronavirus Diagnostic Development_Final3
Technology optimisation
Dependencies
Next steps
Technology optimisation
Research Question
- Continued improvement of technologies
Research Gaps and Challenges
- Decrease time and costs
- Knowledge on antibody-based/serological cross-reactivity between CoVs
- Improve Pan CoVs tests
- Improve NGS technologies and bioinformatics analysis
- Pen-side applications for rapid diagnostics, particularly in low-resource settings
- Interpretation of technologies/assay results in different host species
Solution Routes
- RNA and serological assay combined
- Benchmark gold standard versus new tech
- Public-private partnership
- Improve NGS for easier usage in the field and affordable costs
- Facilitate bio-informatic data sharing; facilitate typing
Dependencies
- Continue to harmonize protocols and adapt new technologies
- Sample collection and transportation independent of cold chain
- Provide reference materials and clinical material for sharing – Nagoya protocol problems with sharing local lab capacity
- Reduce costs of PCR based assays to increase use
- Public/private partnership
Projects
What activities are planned or underway?
Differential susceptibility of SARS-CoV-2 in animals : Evidence of ACE2 host receptor distribution in companion animals, livestock and wildlife by immunohistochemical characterisation
Planned Completion date 26/07/2021
Participating Country(s):
Netherlands
Veterinary Biocontained facility Network for excellence in animal infectiology research and experimentation
Planned Completion date 28/02/2023
Participating Country(s):
Europe