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Coronaviruses roadmap:
Diagnostic Tests

Roadmap for the development of diagnostic tests for coronaviruses

Download 202410 Draft Coronavirus Diagnostic Development_Final

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Technology optimisation

Technology optimisation

Research Question

  • Continued improvement of technologies

Research Gaps and Challenges

  • Decrease time and costs
  • Knowledge on antibody-based/serological cross-reactivity between CoVs
  • Improve Pan CoVs tests
  • Improve NGS technologies and bioinformatics analysis
  • Pen-side applications for rapid diagnostics, particularly in low-resource settings
  • Interpretation of technologies/assay results in different host species

Solution Routes

  • RNA and serological assay combined
  • Benchmark gold standard versus new tech
  • Public-private partnership
  • Improve NGS for easier usage in the field and affordable costs
  • Facilitate bio-informatic data sharing; facilitate typing

Dependencies

  • Continue to harmonize protocols and adapt new technologies
  • Sample collection and transportation independent of cold chain
  • Provide reference materials and clinical material for sharing – Nagoya protocol problems with sharing local lab capacity
  • Reduce costs of PCR based assays to increase use
  • Public/private partnership