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Coronaviruses roadmap:
Control Strategies

Roadmap for the development of disease control strategies for coronaviruses

Download 202410 Draft Coronavirus Disease control research roadmap Final

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Contact networks

Contact networks and quantified transmission pathways (R0)

Research Question

  • Understanding and quantifying the contact networks and transmission pathways of coronaviruses, particularly how they contribute to the spread of the virus within populations

Research Gaps and Challenges

  • Lack of knowledge on host susceptibility, virus circulation and general wildlife disease occurrence making it difficult to spot deviations from transmission trends and identify the cause of any unusual disease outbreaks
  • Asymptomatic and pre-symptomatic transmission can introduce challenges in identifying infectious animals
  • Differences in susceptibility and transmission between host species makes understanding and predicting transmission networks challenging
  • Understanding the role of intermediate “hosts” which act as fomites, such as rodents or wild birds, for onward transmission
  • The population structures/densities and social behaviour of wildlife animals is not well understood therefore it’s difficult to develop accurate contact networks that reflect in situ transmission
  • Existence of undocumented/informal or illegal wildlife trade means that a proportion of transmission will also be unaccounted

Solution Routes

  • Investing resources to study transmission pathways, particularly at the human/wildlife/domestic interphase
  • Continuous improvement of current models available, feeding in new data as it emerges
  • Developing better understanding of animal social behaviours, especially in wildlife animals and learn how to use this data to parameterise models
  • Identify wildlife strains of coronaviruses, sequence them and measure the importance of circulating strains in wildlife to infer potential impacts for transmission of emerging viruses/VOCs

Dependencies

  • The creation of efficient surveillance systems for coronaviruses, which includes establishing access to technologies in local settings
  • Creating and sharing a dataset of viruses and their corresponding susceptible host species

State Of the Art