Coronaviruses roadmap:
Control Strategies
Roadmap for the development of disease control strategies for coronaviruses
Download 202410 Draft Coronavirus Disease control research roadmap Final10
Co-infection
Next steps
Co-infection
Research Gaps and Challenges
- Co-infection with similar/multiple pathogens and/or viral recombination can influence transmission dynamics and confound diagnostics
- It is possible for an organism to become reinfected with the same isolate or strain
- Treatment and recovery in multi-pathogen infection can be challenging due to contraindications or emergence of AMR bacteria – super infections
Solution Routes
- Whole genome sequencing (metagenomics/virome sequencing) – balancing short and long read sequencing techniques depending on the question being asked
- Use of alternative antibiotics or immunopotentiation agents e.g. probiotics, phage viruses, nanoparticles for treatment
Dependencies
- There is a need to understand what the normal host virome/ microbiome is
- Availability of effective alternatives to antibiotics
Projects
What activities are planned or underway?
Differential susceptibility of SARS-CoV-2 in animals : Evidence of ACE2 host receptor distribution in companion animals, livestock and wildlife by immunohistochemical characterisation
Planned Completion date 26/07/2021
Participating Country(s):
Netherlands
Veterinary Biocontained facility Network for excellence in animal infectiology research and experimentation
Planned Completion date 28/02/2023
Participating Country(s):
Europe