Coronaviruses roadmap:
Control Strategies
Roadmap for the development of disease control strategies for coronaviruses
Download 202410 Draft Coronavirus Disease control research roadmap FinalC
Humans
Humans
Research Question
- Mitigate potential spill-over from (and to) animals, including pets, wildlife, and livestock
Research Gaps and Challenges
- Predicting the next ‘jump’ of species
- Pets are a risk as well as wildlife and livestock
- Socio-economic challenges
- Environmental degradation, increased housing and disruption can lead to human disease
- Consideration of dual-use activities and intentional release which threatens safe research
- Methods to differentiate between intentional/deliberate and natural spill over
Solution Routes
- Quantify risk of animal product consumption for emergence of variants of public health concerns
- Identify high-risk interfaces between humans and wildlife
- Identifying changes in the virus in crossover to humans
Dependencies
- Cross-sector working across environment, health, housing, etc.
- Ensure laboratory biosecurity standards are maintained
- Trade of live animals of high-risk species should be avoided and/or highly controlled
State Of the Art
- SARS‐CoV, MERS‐CoV and SARS‐CoV‐2 had involved domestic or wildlife animal as reservoir or as intermediate host
Projects
What activities are planned or underway?
Differential susceptibility of SARS-CoV-2 in animals : Evidence of ACE2 host receptor distribution in companion animals, livestock and wildlife by immunohistochemical characterisation
Planned Completion date 26/07/2021
Participating Country(s):
Netherlands
Veterinary Biocontained facility Network for excellence in animal infectiology research and experimentation
Planned Completion date 28/02/2023
Participating Country(s):
Europe