Roadmap for the development of diagnostic tests for FMD

What are we trying to achieve and why? What is the problem we are trying to solve?

To develop reliable and rapid immunological tests allowing to identify peri-clinical, subclinically infected, and recovered animals.

What are the scientific and technological challenges
(knowledge gaps needing to be addressed)?

• Identify peri-clinical, subclinical and carrier animals
• Need for serological test to show recovery (absence of circulating virus)
• Develop serotype specific rRT-PCR assay(s)
• Generate immunological reagents for testing wildlife

What else needs to be done before we can solve this need?

Immune response.

Existing knowledge including successes and failures

The use of recombinant technology as an alternative source of test antigens has shown promise in several studies.