Home African Swine Fever [Detection of host response] Detection of host response
African Swine Fever roadmap:
Diagnostic Tests

Roadmap for the development of diagnostic tests for ASF

Download ASF Diagnostic Roadmap

3

Detection of host response

Dependencies

  • 4 Expression system

Next steps

Develop diagnostic indirect tests for the detection of the disease

Research Question

  • The development of diagnostic tests able to reliably detect low titres of antibodies and of new assays based on cellular immunity for the detection of the disease

Research Gaps and Challenges

  • Varying host immune response to the virus between both virus’ isolates and host species
  • Testing of bad quality wild boar sera
  • Laboratory capacities (variability of results among laboratories)

State Of the Art

  • Knowledge was gained and collated on suitable antigens and their expression for serodiagnosis of ASF. Five serological methods were recently tested, including three commercial  ELISAs, the OIE-ELISA, and the confirmatory immunoperoxidase test (IPT)

Projects

What activities are planned or underway?

African Swine Fever virus inactivation by feed additives in vitro

Planned Completion date 01/01/2022

Source Countries:

NetherlandsIconNetherlands

The incursion risk of African swine fever for the Netherlands by human-mediated routes

Planned Completion date 01/01/2022

Source Countries:

NetherlandsIconNetherlands