Foot and Mouth Disease roadmap:
Diagnostic Tests
Roadmap for the development of diagnostic tests for FMD
Download FMD Diagnostic_Lead Summaries_Roadmap update3
Tools
Development of expression systems for FMD diagnostic reagents
Research Question
What are we trying to achieve and why? What is the problem we are trying to solve?
To develop expression system for FMD diagnostic reagents that would not require specialised biosafety level 3 facilities to be produced securely.
Research Gaps and Challenges
What are the scientific and technological challenges
(knowledge gaps needing to be addressed)?
- Develop simple methods for RNA extraction
- Identify new expression systems
State Of the Art
What else needs to be done before we can solve this need?
The use of recombinant technology as an alternative source of test antigens has shown promise in several studies.
Projects
What activities are planned or underway?
Practical surveillance guidelines for the progressive control of Food-and-Mouth Disease and other transboundary animal diseased
Planned Completion date 20/09/2024
Source Countries:
Netherlands
Foot-and-mouth disease virus antigenic landscape and reduced immunogenicity elucidated in atomic detail.
Planned Completion date 10/10/2024
Source Countries:
Netherlands