Home African Swine Fever [Genome detection] Improving sequencing of ASF genome
African Swine Fever roadmap:
Diagnostic Tests

Roadmap for the development of diagnostic tests for ASF

Download ASF Diagnostic Roadmap

10

Genome detection

Dependencies

  • 14 Sample collection/ transport/ preparation

Next steps

Improving sequencing of ASF genome

Research Question

  • The complete sequencing of 1-3 isolates from each genotype, a series of viruses (>10) with different virulence and, a series of viruses (>5) that have replicated exclusively in domestic pigs, wild pigs and ticks

Research Gaps and Challenges

  • Optimised and harmonised workflows are needed for next-generation sequencing

State Of the Art

  • Using current, very robust technologies, it has been possible to develop a comprehensive database, which includes full length genome sequence of large number of isolates to replace the current less meaningful genotype-based classification: https://virology.uvic.ca/organisms/dsdnaviruses/asfarviridae/

Projects

What activities are planned or underway?

Africa's Long Depression: The Growth and Debt Crises of 1975-2000

Planned Completion date 01/03/2027

Participating Country(s):

United KingdomIconUnited Kingdom