Home Coronaviruses [Host-pathogen-environment interactions] Host-pathogen-environment interactions
Coronaviruses roadmap:
Control Strategies

Roadmap for the development of disease control strategies for coronaviruses

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Host-pathogen-environment interactions

Host-pathogen-environment interactions

Research Question

  • Improve understanding of host-pathogen-environment interactions in order to implement effective control

Research Gaps and Challenges

  • There is a need to understand the role and impact different environmental factors play in disease development and emergence. This should consider how different land uses and animal husbandry practices influence the emergence and spread of infections
  • There is a need to understand different transmission pathways and the circumstances that may led to emergence of infections in wildlife and livestock
  • It is difficult to identify and prevent interaction [of coronaviruses] with wildlife

Solution Routes

  • Modelling studies and transmission studies in vitro, ex vivo and vivo
  • Modelling future land-use and agricultural practises scenarios
  • Targeted field research to better understand potential pathways of transmission amongst wildlife, livestock and humans

Dependencies

  • Identification of appropriate wildlife hosts
  • Collecting of data as a resource to facilitate modelling
  • Citizen education on how to avoid/manage potential high-risk wildlife-humans interactions
  • Increase understanding of host differences in infectivity, immune responses, and pathogenesis. In particular, in bats and other animal species that are known to host CoVs

State Of the Art