Home African Swine Fever [Host range] Defining ASF host range
African Swine Fever roadmap:
Control Strategies

Roadmap for the development of control strategies for ASF

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Host range

Host range

Research Question

  • Feral swine and wild suidae may have an important role in the spread and maintenance of ASF. The potential role of these species as a reservoir for ASF should be further investigated

Research Gaps and Challenges

  • Identify ASFV genes and genetic determinants (group of genes like multigene families) involved in host range, virulence and pathogenicity
  • Study the pathogenesis of ASFV isolates with different virulence in diverse susceptible host

State Of the Art

  • ASF is a contagious viral disease of domestic pigs In Africa, ASF virus (ASFV) produces unapparent infections in wild suids: wart hog (Phacochoerus africanus), bush pigs (Potamochoerus
    larvatus, P. porcus) and the giant forest hog (Hylochoerus meinertzhageni) (a single report). The reservoir of ASFV is considered the soft tick Ornithodoros moubata.
  • The virus Georgia 2007 affects both domestic pigs and European wild boar, with the latter proving to be as susceptible as domestic pigs and the disease established selfsustaining cycles within the wild boar population. This was unprecedented as so far, any previous introduction into the European wild boar population had been self-limiting, unless sustained by co-infection and spillover from domestic pigs. It is increasingly apparent that the terminal genomic regions and Multigene Family (MGF) genes play a significant role in ASFV host range

Projects

What activities are planned or underway?

Africa's Long Depression: The Growth and Debt Crises of 1975-2000

Planned Completion date 01/03/2027

Participating Country(s):

United KingdomIconUnited Kingdom