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Diagnostic Tests

Roadmap for the development of diagnostic test for influenza

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5

Host response

Dependencies

Next steps

Host response

Research Question

  • Identify a measurable host response

Research Gaps and Challenges

  • Complexity of interwoven factors
  • Inherent variability of maternal antibodies
  • Varying types of antibodies, deltaFcIgY and their roles, mucosal immunity
  • Need for animal models in the laboratory
  • Many different wild bird species as a host to understand

Solution Routes

  • Antibody detection vs. Protection, methods for hi throughput HIs?
  • Other?
  • Utility of in vitro systems

Dependencies

  • Avian immunology for various species
  • Understanding of the immune system of migrating birds
  • Research facilities that can house dams, mares, hens and not just their offspring
  • Understanding the nature and effectors of resilient AIV immunity
  • Factors that contribute to failure to mount such immune responses in a species-dependent manner

Projects

What activities are planned or underway?

Protect wildlife from livestock diseases.

Planned Completion date 07/10/2022

Participating Country(s):

NetherlandsIconNetherlands

Impact of host age on viral and bacterial communities in a waterbird population.

Planned Completion date 01/11/2022

Participating Country(s):

NetherlandsIconNetherlands