Influenza roadmap:
Diagnostic Tests
Roadmap for the development of diagnostic test for influenza
Download Influenza-diagnostic-development-roadmapB
Cell mediated immunity
Cell-mediated immunity
Research Question
- Diagnose the presence and valence of cell-mediated immunity against AIV
Research Gaps and Challenges
- High laboratory specialization and technical skills of staff required
- Limited understanding of variation of mechanisms between species and viral strains
- Need for specific equipment to measure immune cells (I.e.: FACS, etc)
- Variable genetic backgrounds of host (I.e.: commercial breeds versus backyard stocks)
Solution Routes
- Develop technically undemanding and cost-effective tools to define (parts) of CMI
- Role of cell-mediated immunity (CMI) in individual animal recovery and outbreak outcomes
- Tools to define immune cell populations in avian species
- Test to predict cell mediated levels and correlate with vaccine protection
Dependencies
- Basic data on the development of cellular immune effectors in various avian species
- Research facilities that can hold animals for a long period of time (months) to determine if CMI is protective against heterologous challenge
Projects
What activities are planned or underway?
Protect wildlife from livestock diseases.
Planned Completion date 07/10/2022
Participating Country(s):
Netherlands
Dynamics of sustainability in integrated agriculture : aquaculture systems in the Mekong Delta
Planned Completion date 21/10/2024
Participating Country(s):
Netherlands