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Roadmap for the development of candidate vaccines for influenza

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Identity of immunomodulators

Identity of immunomodulators

Research Question

  • Identity of main immunomodulators

Research Gaps and Challenges

  • Lack of knowledge of main roles of virus immunomodulators

Solution Routes

  • Standardized protocols for a set of cytokines to go with regular
    qPCR/titration assays

Dependencies

  • What else needs to be done before we can solve this need?
  • Better understanding of innate immunity in birds, swine, equine,
    canine
  • Role of prior exposure to other pathogens that might limit the host
    response to vaccination(e.g. Virus combinations)
  • Correlates of protection and effects of immunomodulators (some use just classical assays ie. HI)

Projects

What activities are planned or underway?

Protect wildlife from livestock diseases.

Planned Completion date 07/10/2022

Participating Country(s):

NetherlandsIconNetherlands

Impact of host age on viral and bacterial communities in a waterbird population.

Planned Completion date 01/11/2022

Participating Country(s):

NetherlandsIconNetherlands