Roadmap for Immunomodulators

What are we trying to achieve and why? What is the problem we are trying to solve?

Better define how inflammation negatively impact on the animals.

What are the scientific and technological challenges (knowledge gaps needing to be addressed)?

Establish incitants and pathways of inflammation to abiotic and biotic factors in livestock animals.
Explore if reducing inflammation has a negative impact on the disease outcome on the animals.
Role of stress on immune response/inflammation.
Role of hormones on immune response/inflammation.

What approaches could/should be taken to address the research question?

Platforms for monitoring host responses (e.g., PCR, ELISA, OMICs).
Measurement of cytokine/chemokine expression is key.
Monitoring interactions between immunomodulators and microbiota.
Histology or tissue effects.

What else needs to be done before we can solve this need?

Existing knowledge including successes and failures