Roadmap for Immunomodulators

What are we trying to achieve and why? What is the problem we are trying to solve?

Identifying how the immune response can been modified to enhance resistance.

What are the scientific and technological challenges (knowledge gaps needing to be addressed)?

Lack of specific reagents.
Lack of knowledge.

What approaches could/should be taken to address the research question?

Cytokine responses.
Cellular responses.
System approach.
MOA (Mechanism of Action).
Multi-omic-approach.
(interaction with receptors TRLs).

What else needs to be done before we can solve this need?

Existing knowledge including successes and failures