Influenza roadmap:
Diagnostic Tests
Roadmap for the development of diagnostic test for influenza
Download Influenza-diagnostic-development-roadmap9
Organism detection
Organism detection
Research Question
- Detection of influenza viruses in various species and matrices including environmental sources
Research Gaps and Challenges
- Sensitivity of detection versus specificity versus contamination risks
- Cost effectiveness, commercialization
- How many/much samples are needed to determine prevalence/risk?
- I.e.: pools, environmental samples, versus direct from animal
Solution Routes
- Sampling methods and transport for low resource settings
- Assessment of local need to reach acceptable confirmatory diagnosis
- Implementation of routine targeted testing for endemic IAVs that can be scaled up during an outbreak and/or serve as background data when a new IAV strain emerges or is a concern
- Validate and verify novel solutions (field PCR, LAMP, etc) for in-field and laboratory methods
- Standardize diagnostics from environmental samples
- Surveillance sensitivity should be decided
- Protocols to work through co-infections in order to capture all pathogens
- Rapid sensitive and specific methods for field detection (subtype specific if possible?)
Dependencies
- Clear country requirements for diagnostic (matrices and species)
- Defining diagnostic needs according to region, poultry vs wild birds vs livestock vs humans etc
- Understanding IAV ecology for a location/system in order to target surveillance
Projects
What activities are planned or underway?
Protect wildlife from livestock diseases.
Planned Completion date 07/10/2022
Participating Country(s):
Netherlands
Dynamics of sustainability in integrated agriculture : aquaculture systems in the Mekong Delta
Planned Completion date 21/10/2024
Participating Country(s):
Netherlands