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Influenza roadmap:
Diagnostic Tests

Roadmap for the development of diagnostic test for influenza

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Organism detection

Organism detection

Research Question

  • Detection of influenza viruses in various species and matrices including environmental sources

Research Gaps and Challenges

  • Sensitivity of detection versus specificity versus contamination risks
  • Cost effectiveness, commercialization
  • How many/much samples are needed to determine prevalence/risk?
  • I.e.: pools, environmental samples, versus direct from animal

Solution Routes

  • Sampling methods and transport for low resource settings
  • Assessment of local need to reach acceptable confirmatory diagnosis
  • Implementation of routine targeted testing for endemic IAVs that can be scaled up during an outbreak and/or serve as background data when a new IAV strain emerges or is a concern
  • Validate and verify novel solutions (field PCR, LAMP, etc) for in-field and laboratory methods
  • Standardize diagnostics from environmental samples
  • Surveillance sensitivity should be decided
  • Protocols to work through co-infections in order to capture all pathogens
  • Rapid sensitive and specific methods for field detection (subtype specific if possible?)

Dependencies

  • Clear country requirements for diagnostic (matrices and species)
  • Defining diagnostic needs according to region, poultry vs wild birds vs livestock vs humans etc
  • Understanding IAV ecology for a location/system in order to target surveillance

Projects

What activities are planned or underway?

Protect wildlife from livestock diseases.

Planned Completion date 07/10/2022

Participating Country(s):

NetherlandsIconNetherlands

Dynamics of sustainability in integrated agriculture : aquaculture systems in the Mekong Delta

Planned Completion date 21/10/2024

Participating Country(s):

NetherlandsIconNetherlands