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African Swine Fever roadmap:
Diagnostic Tests

Roadmap for the development of diagnostic tests for ASF

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13

Organism isolation

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Dependencies

  • 14 Sample collection/ transport/ preparation

Next steps

Investigating alternative sample types for ASF diagnosis

Research Question

  • Identify suitable sample types allowing for more environmental and less invasive diagnostic, and for easier and lower risk sample exchange

Research Gaps and Challenges

  • Full validation of novel or modified direct and/or indirect tests in alternative sample types (e.g. blood, exudate´s tissues, oral fluids, meat juice, filter papers, swabs), including nonclinical ones (e.g. soil, straw, pork products, bad quality samples from wild animals)
  • Development and evaluation of non-invasive sampling methodologies in wild suids
  • Using sampling protocols to collect samples which ease to exchange between the countries (i.e. no biorisk samples)

Solution Routes

  • To improve reagent stability, different strategies such as lyophilization could be explored

State Of the Art

  • The field of diagnostics has expanded into the search for new models of detection, including for new types of samples like faeces, FTA cards, dry blood swabs, and oral fluids, but also searching for new models as air samples and feed

Projects

What activities are planned or underway?

African Swine Fever virus inactivation by feed additives in vitro

Planned Completion date 01/01/2022

Source Countries:

NetherlandsIconNetherlands

The incursion risk of African swine fever for the Netherlands by human-mediated routes

Planned Completion date 01/01/2022

Source Countries:

NetherlandsIconNetherlands