Roadmap for Immunomodulators
Download Alternatives-to-Antibiotics-Report-20224
PRR Agonists
Research Question
What are we trying to achieve and why? What is the problem we are trying to solve?
Identifying PPRs agonists as immunostimulants.
Research Gaps and Challenges
What are the scientific and technological challenges (knowledge gaps needing to be addressed)?
Understanding the TLR signalling and its function.
Understand how to antagonize the harmful effects without affecting host defence functions.
Solution Routes
What approaches could/should be taken to address the research question?
Identify a panel (an array) of PRR
Identify trigger and functions.
Identify PRR, test for function and look for selection.
Dependencies
What else needs to be done before we can solve this need?
State Of the Art
Existing knowledge including successes and failures
Projects
What activities are planned or underway?
outer membrane vesicles protect gram negative bacteria against host defense peptides
Planned Completion date 25/08/2021
Netherlands
Advanced porous materials for antimicrobial treatment
Planned Completion date 31/10/2023
Netherlands