Influenza roadmap:
Diagnostic Tests
Roadmap for the development of diagnostic test for influenza
Download Influenza-diagnostic-development-roadmap10
Sample type/transportation/preparation
Next steps
- 7 Host-pathogen interaction
- 7A Susceptible
- 7B Exposed
- 7C Infectious
- 9 Organism detection
- 9A Direct detection
- 9B Genetic
Sample type/transportation/preparation
Research Question
- Improvement of viral sampling, transportation and isolation of nucleic acids and viruses
Research Gaps and Challenges
- Sampling sparing methods
- Improvement of safe transport of virus
- Pools and matrix of choice for environmental sampling, Virus extraction from environmental matrices (e.g. water, mud, aquatic microfauna, etc.)
- Poultry environs that also include varying types of chemicals
- Limitations defined by CITES (species protection and conservation acts)
- Limitations defined by the NAGOYA protocol (WHO exemptions etc.)
- Preserve the quality and viability of biological samples during transportation over long distances and temperature extremes
Solution Routes
- In-field extraction and diagnostics (PoC/Penside) to minimize transport
- Development of transport media that stabilize the virus without refrigeration
- Non-invasive samples from wild birds
- Non-invasive samples from swine
- Environmental sampling methods including
– Air sampling and analysis protocols
– Waste water
– Poultry house sampling, where are the best samples
Dependencies
- Standardize environmental sampling procedures
- Easy legal frameworks for transport
- Manageable CITES and NAGOYA rules for avian samples
- Data management for sampling/testing coordination
- Human resources
Projects
What activities are planned or underway?
Protect wildlife from livestock diseases.
Planned Completion date 07/10/2022
Participating Country(s):
Netherlands
Dynamics of sustainability in integrated agriculture : aquaculture systems in the Mekong Delta
Planned Completion date 21/10/2024
Participating Country(s):
Netherlands