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Influenza roadmap:
Diagnostic Tests

Roadmap for the development of diagnostic test for influenza

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Sample type/transportation/preparation

Next steps

Sample type/transportation/preparation

Research Question

  • Improvement of viral sampling, transportation and isolation of nucleic acids and viruses

Research Gaps and Challenges

  • Sampling sparing methods
  • Improvement of safe transport of virus
  • Pools and matrix of choice for environmental sampling, Virus extraction from environmental matrices (e.g. water, mud, aquatic microfauna, etc.)
  • Poultry environs that also include varying types of chemicals
  • Limitations defined by CITES (species protection and conservation acts)
  • Limitations defined by the NAGOYA protocol (WHO exemptions etc.)
  • Preserve the quality and viability of biological samples during transportation over long distances and temperature extremes

Solution Routes

  • In-field extraction and diagnostics (PoC/Penside) to minimize transport
  • Development of transport media that stabilize the virus without refrigeration
  • Non-invasive samples from wild birds
  • Non-invasive samples from swine
  • Environmental sampling methods including
    – Air sampling and analysis protocols
    – Waste water
    – Poultry house sampling, where are the best samples

Dependencies

  • Standardize environmental sampling procedures
  • Easy legal frameworks for transport
  • Manageable CITES and NAGOYA rules for avian samples
  • Data management for sampling/testing coordination
  • Human resources

Projects

What activities are planned or underway?

Protect wildlife from livestock diseases.

Planned Completion date 07/10/2022

Participating Country(s):

NetherlandsIconNetherlands

Dynamics of sustainability in integrated agriculture : aquaculture systems in the Mekong Delta

Planned Completion date 21/10/2024

Participating Country(s):

NetherlandsIconNetherlands