Roadmap for Microbiota optimisation

What are we trying to achieve and why? What is the problem we are trying to solve?

Ensuring scientific soundness of technical and analytical approaches for studying the host microbiome (approaches need to be justified and metadata made available).

What are the scientific and technological challenges (knowledge gaps needing to be addressed)?

Harmonised technical and analytical methods for studying host microbiome that are accessible.
Standardised techniques and systems (paying attention to don’t be too picky.
To define standards for assessing antibiotic impact on gut microbiome/dysbiosis, allowing comparative analysis between drug types/classes.
Big data sharing and analysis.

What approaches could/should be taken to address the research question?

Transparency and sharing in the selection/justification of technical and analytical approaches for studying the host microbiome (metadata needs to be made available).
Organ-on-a chip.
Organoids.
Software/supercomputers? For big data analysis.
Networking.

What else needs to be done before we can solve this need?

Existing knowledge including successes and failures