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Bovine Tuberculosis (bTB) roadmap:
Control Strategies

Roadmap for development of disease control strategies for bTB

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Control strategies
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                                                                                  Lead Summary Challenges and gap analysis
                                                                                  1 Control strategies The control of bovine TB progressively leading to disease eradication
                                                                                  2B Stakeholder acceptance Stakeholder acceptability
                                                                                  2A Cost benefits Cost and benefit
                                                                                  2 Socio-economic aspects Socio-economics
                                                                                  3D Disease management Identification of signatures of clinical status at the individual level
                                                                                  3C Bio security Bio security
                                                                                  3B Therapeutics Therapeutics
                                                                                  3A Vaccine Vaccine
                                                                                  3 Control tools
                                                                                  4 Mathematical models Mathematical models
                                                                                  5 Transmission pathways within and between host species Transmission pathways
                                                                                  6 Contact networks Contact networks
                                                                                  7 Host demographics Host demographics - including wildlife hosts
                                                                                  8 R0 R0 (Reproduction Index)
                                                                                  9 Prevalence of disease Prevalence of disease / infection
                                                                                  10 Diagnostics Diagnostics
                                                                                  11 Vector
                                                                                  12 Warning Signal
                                                                                  13 Molecular typing Molecular typing
                                                                                  14 Environment Environment
                                                                                  15C Resistant cleared HPI – Resistant/cleared : the role of innate immunity
                                                                                  15B Latent carrier HPI – latent/carrier: identification of signatures of clinical status at the individual level
                                                                                  15A Active infection HPI - Active infection
                                                                                  15 Host-pathogen-environment interactions Host-pathogen interactions
                                                                                  16 Coinfection Coinfection
                                                                                  17 Host range Host range
                                                                                  18 Host genetics Genetic selection
                                                                                  19 Pathogen genome Pathogen genome