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Antimicrobial Resistance and Alternatives to Antimicrobials roadmap:
Control Strategies

Roadmap for Phage technologies

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Screening for absence of undesirable genes
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    Phage technology for pathogens control
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      Lytic Phage
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        Phage technology for pathogens control
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          Phage as an adjunct to other therapies
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            Phage technology for pathogens control
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              Phage as delivery vehicle"] --> 22815["

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              Phage technology for pathogens control
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                Phage Selection
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                  Phage as an adjunct to other therapies
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                    Phage Selection
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                      Screening for absence of undesirable genes
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                        Phage production by Synthetic biology
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                          Phage as delivery vehicle"] 22824["

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                          Understanding of Phage-Pathogen interaction including life cycle, bindings sites etc.
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                            Phage Selection
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                              Understanding of Phage-Pathogen interaction including life cycle, bindings sites etc.
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                                Phage production by Synthetic biology
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                                  Phage Isolation
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                                    Understanding of Phage-Pathogen interaction including life cycle, bindings sites etc.
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                                      Understanding of Phages in the relevant environment (including source animals)
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                                        Phage Isolation
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                                          Lead Summary Challenges and gap analysis
                                          1 Phage technology for pathogens control Pathogen control using phage technology
                                          2 Screening for absence of undesirable genes Screening for absence of undesirable genes
                                          3 Lytic Phage Phage as an adjunct to other therapies
                                          4 Phage as an adjunct to other therapies Lytic Phages
                                          5B Phage as delivery vehicle for therapies (Ab, AMP etc.) Phage as delivery vehicle for therapies (Ab, AMP etc.)
                                          5A Phage to deliver genetic material to disrupt AMR plasmids or virulence factors Phage to deliver genetic material to disrupt AMR plasmids or virulence factors
                                          5 Phage as delivery vehicle Phage as delivery vehicle
                                          6 Phage Selection Phage Selection
                                          7 Phage production by Synthetic biology Phage production by Synthetic biology
                                          8 Understanding of Phage-Pathogen interaction including life cycle, bindings sites etc. Understanding of Phage-Pathogen interaction including life cycle, bindings sites etc.
                                          9 Phage Isolation Phage Isolation
                                          10 Understanding of Phages in the relevant environment (including source animals) Understanding of Phages in the relevant environment/phage ecology