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Helminths (including anthelmintic resistance) roadmap:
Control Strategies

Roadmap for the development of control strategies for liver fluke

Download Liver-Fluke-Control-Strategy-Roadmap-1
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                                                                                  Lead Summary Challenges and gap analysis
                                                                                  1 Control strategies The sustainable control of Fasciola hepatica, minimising production loss while maintaining efficacy of therapeutics
                                                                                  2B Stakeholder acceptance Sociologic evaluation to understand user needs and acceptance of control strategies against liver fluke
                                                                                  2A Cost benefits Economic evaluation of current and future control strategies against liver fluke
                                                                                  2 Socio-economic aspects
                                                                                  3D Disease management Integrated control through pasture management and other control option
                                                                                  3C Bio security Preventing the introduction of AR parasites
                                                                                  3B Therapeutics Sustainable use of flukicides
                                                                                  3A Vaccine Requirements and use strategy for liver fluke vaccines
                                                                                  3 Control tools
                                                                                  4 Mathematical models Mathematical models of liver fluke for prediction and control
                                                                                  5 Transmission pathways within and between host species Role of the intermediate hosts in liver fluke epidemiology
                                                                                  6 Contact networks Role of livestock movements and wildlife reservoirs
                                                                                  7 Host demographics Animal characteristics
                                                                                  8 R0 Parasite population amplification and its contribution to disease risk
                                                                                  9 Prevalence of disease Liver fluke prevalence
                                                                                  10 Diagnostics Liver fluke diagnostics
                                                                                  11 Vector Biology of the intermediate host snails
                                                                                  12 Warning Signal Early warning systems for liver fluke
                                                                                  13 Molecular typing Molecular epidemiology
                                                                                  14 Environment Environmental influences on liver fluke epidemiology
                                                                                  15C Resistant cleared Protective immune response to Fasciola hepatica
                                                                                  15B Latent carrier Can animals be resilient to liver fluke infection?
                                                                                  15A Active infection How does immunity develop against F. hepatica?
                                                                                  15 Host-pathogen-environment interactions
                                                                                  16 Coinfection Implications of co-infection for control of liver fluke
                                                                                  17 Host range How does the range and relative competence of definitive and intermediate host species affect the epidemiology of Fasciola hepatica?
                                                                                  18 Host genetics Host genetic factors influencing Fasciola hepatica infection
                                                                                  19 Pathogen genome Liver fluke genome