Home Foot and Mouth Disease Roadmap for the research to underpin the development of control strategies for FMD
Foot and Mouth Disease roadmap:
Control Strategies

Roadmap for the research to underpin the development of control strategies for FMD

Download FMD Control Strategy Roadmap
--- config: theme: default defaultRenderer: 'elk' themeVariables: lineColor: "red" --- flowchart LR 21416["

2

Socio-economic aspects"] --> 21420["

1

Control strategies
    "] 21432["

    5

    Contact networks and qualified transmission pathways
      "] --> 21423["

      3

      Control tools"] 21423["

      3

      Control tools"] --> 21416["

      2

      Socio-economic aspects"] 21423["

      3

      Control tools"] --> 21425["

      4

      Modelling interventions
        "] 21423["

        3

        Control tools"] --> 21432["

        5

        Contact networks and qualified transmission pathways
          "] 21425["

          4

          Modelling interventions
            "] --> 21423["

            3

            Control tools"] 21425["

            4

            Modelling interventions
              "] --> 21416["

              2

              Socio-economic aspects"] 21432["

              5

              Contact networks and qualified transmission pathways
                "] --> 21425["

                4

                Modelling interventions
                  "] 21433["

                  6

                  Prevalence and cost of disease
                    "] --> 21432["

                    5

                    Contact networks and qualified transmission pathways
                      "] 21433["

                      6

                      Prevalence and cost of disease
                        "] --> 21423["

                        3

                        Control tools"] 21434["

                        7

                        Diagnostics
                          "] --> 21433["

                          6

                          Prevalence and cost of disease
                            "] 21435["

                            8

                            Warning signal and monitoring
                              "] --> 21433["

                              6

                              Prevalence and cost of disease
                                "] 21435["

                                8

                                Warning signal and monitoring
                                  "] --> 21434["

                                  7

                                  Diagnostics
                                    "] 21436["

                                    9

                                    Host-pathogen-environment interactions"] --> 21435["

                                    8

                                    Warning signal and monitoring
                                      "] 21438["

                                      10

                                      Coinfection
                                        "] --> 21436["

                                        9

                                        Host-pathogen-environment interactions"] 21441["

                                        11

                                        Host range"] --> 21436["

                                        9

                                        Host-pathogen-environment interactions"] 21443["

                                        12

                                        Environment including farming system
                                          "] --> 21432["

                                          5

                                          Contact networks and qualified transmission pathways
                                            "] 21443["

                                            12

                                            Environment including farming system
                                              "] --> 21441["

                                              11

                                              Host range"] 21447["

                                              13

                                              Host genetics
                                                "] --> 21441["

                                                11

                                                Host range"] 21448["

                                                14

                                                Pathogen genome
                                                  "] --> 21441["

                                                  11

                                                  Host range"] linkStyle default stroke-width:1px,stroke:#3bcaf2
                                                  Lead Summary Challenges and gap analysis
                                                  1 Control strategies Development of effective and sustainable control strategies for FMD
                                                  2B Stakeholder acceptance Stakeholder acceptance of new generation of improved FMD control strategies
                                                  2A Cost benefits Costs-benefits of FMD control strategies
                                                  2 Socio-economic aspects Social and economic impacts of the new generation of improved FMD control strategies
                                                  3E Pathogen inactivation Pathogen inactivation
                                                  3D Genetic selection
                                                  3C Bio security Assessment of biosafety risk of shipping penside tests containing inactivated FMDV
                                                  3B Therapeutics Effective bio-therapeutics
                                                  3A Vaccine
                                                  3 Control tools Development of improved control tools against FMD
                                                  4 Modelling interventions Modelling interventions
                                                  5 Contact networks and qualified transmission pathways Quantification of FMD transmission pathways (R0)
                                                  6 Prevalence and cost of disease Evaluation of FMD burden
                                                  7 Diagnostics
                                                  8 Warning signal and monitoring Warning signal and monitoring
                                                  9C Resistant cleared Establishment of the immune mechanisms underlying protection to FMDV
                                                  9B Latent carrier Determination of mechanisms of FMDV persistence in livestock and role in transmission
                                                  9A Active infection Understanding virus host interactions during early phases of FMD infection
                                                  9 Host-pathogen-environment interactions Elucidation of the FMD host-pathogen-microbiome-environment interactions
                                                  10 Coinfection Investigation of multiple infection and viral competition
                                                  11D Vector
                                                  11C Humans
                                                  11B Livestock Livestock
                                                  11A Wildlife Definition of the role of wildlife and persistent infection in FMD endemic settings
                                                  11 Host range Determination of host-range and role of the different species on long-term maintenance of FMDV
                                                  12 Environment including farming system Improving the knowledge of transhumance and dynamic of FMDV
                                                  13 Host genetics
                                                  14 Pathogen genome Pathogen genome